Hepatitis B, Hepatitis B (HBcAb), Hepatitis B Antigen e (HBeAg), Hepatitis B Antibodies E, Hepatitis B Surface Antibodies. (Anti-HBS)
Hepatitis B virus (HBV) testing plays an important role in detection, classification, and management of HBV disease.
Results of HBV serologic markers can be reported qualitatively or quantitatively as international units (IU) or signal per cutoff (s/c) value. For example, a hepatitis B surface antigen (HBsAg) level of less than 1 s/c is considered negative, while a level more than 5 s/c is considered positive. Any value between 1 and 5 s/c is indeterminate and should be repeated. For hepatitis B surface antibody (anti-HBs), a level less than 5 mIU is considered negative, while a level more than 12 mIU is considered protective. Any value between 5 and 12 mIU is indeterminate and should be repeated.
These following reference ranges are based on qualitative measurement of serologic markers in an asymptomatic, nonimmunized population.
- HBsAg: Negative
- Anti-HBs: Negative; a level of greater than 10-12 mIU/mL is protective
- Immunoglobulin M (IgM) hepatitis B core antibody (anti-HBc): Negative
- Immunoglobulin G (IgG) anti-HBc: Negative
- Hepatitis B e-antigen (HBeAg): Negative
- Hepatitis B e-antibody (anti-HBe): Negative
- HBV DNA: Negative
- Sample of blood serum
- We perform the test daily