Risk assessment for Alzheimer’s disease (AD2)

Alzheimer’s disease is genetically heterogeneous and is a multigene disorder, presenting characteristic symptoms of progressive dementia with pervasive cerebral atrophy. It has been estimated that 5% of all individuals over the age of 70 years are suffering from this disorder. Even though genes directly responsible for all types of this disorder have not yet been identified, it is already clear that there is a strong correlation between this disorder and the e4 allele of the ApoE gene.