This type of analysis can be applied from cells of various tissues, in cases where a rapid detection of aneuploidy for chromosomes 13, 18, 21, X and Y is required. A small amount of tissue material is adequate (1-2 ml of amniotic fluid or a small amount of blood).
This test cannot reliably detect mosaicism and is not a substitute of classic cytogenetic analysis. It will detect the most common chromosomal abnormalities encountered during pregnancy. It cannot be applied in samples contaminated with other tissue (for example, a bloody amniotic fluid sample or CVS contaminated with maternal cells).