C1 esterase inhibitor

C1 esterase inhibitor (C1-INH) is a protein found in the fluid part of your blood. It controls a protein called C1, which is part of the complement system. This system is a group of proteins that move freely through your bloodstream. The proteins work with your immune system and play a role in the development of inflammation. There are nine major complement proteins. They are labeled C1 through C9.

Complement factors are very important in testing for autoimmune diseases, especially systemic lupus erythematosus. Low levels of C1-INH can lead to a condition called angioedema. Angioedema results in sudden swelling of the tissues of the face, upper throat and tongue and may cause difficulty breathing. Swelling in the intestine and abdominal pain may also occur. There are two types of conditions that cause angioedema from decreased levels of C1-INH. They are known as hereditary and acquired C1-INH deficiency.

  • Sample of blood serum
  • We perform the test in 24 hours from sampling