Beta-2-glycoprotein I antibodies (IgG, IgA, IgM)

Beta-2 glycoprotein 1 antibody tests are used along with cardiolipin antibody and lupus anticoagulant testing to help diagnose the cause of an unexplained blood clot (thrombotic episode) or recurrent miscarriages, to help diagnose antiphospholipid syndrome (APS), or to detect the autoantibodies in someone with another autoimmune disorder.

Antiphospholipid antibodies, including beta-2 glycoprotein anitboides, are associated with excessive clotting. They interfere with the body’s blood clotting process in a way that is not fully understood.

Laboratory tests can detect three different classes of these autoantibodies: IgG, IgM, and IgA. If all three of the initial antiphospholipid antibody tests for the IgG and IgM classes are negative but APS is still suspected, then the IgA class of these antibodies may be tested, along with other less common antiphospholipid antibodies, such as anti-phosphatidylserine and anti-prothrombin.

  • Sample of blood serum
  • We perform the test every Tuesday & Friday